Topological Constraints on Transvection Between white Genes Within the Transposing Element TE35B in Drosophila melanogaster
نویسندگان
چکیده
منابع مشابه
Transvection at the vestigial locus of Drosophila melanogaster.
Transvection is a phenomenon wherein gene expression is effected by the interaction of alleles in trans and often results in partial complementation between mutant alleles. Transvection is dependent upon somatic pairing between homologous chromosome regions and is a form of interallelic complementation that does not occur at the polypeptide level. In this study we demonstrated that transvection...
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HE X-linked white locus of Drosophila melanogaster is a complex region of Tthe chromosome which has been subdivided into a number of sites (LEWIS 1952; MACKENDRICK and PONTECORVO 1952; GREEN 1959, 1964; JUDD 1959, 1964). Heterozygotes for two mutant alleles mapping at different sites in the white region (except for compounds with the right-most site, for white-spotted) do not show complementati...
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The symbiotic relationship between the mitochondrial and nuclear genomes coordinates metabolic energy production and is fundamental to life among eukaryotes. Consequently, there is potential for strong selection to shape interactions between these two genomes. Substantial research attention has focused on the possibility that within-population sequence polymorphism in mitochondrial DNA (mtDNA) ...
متن کاملEffects of chromosomal rearrangements on transvection at the yellow gene of Drosophila melanogaster.
Homologous chromosomes are paired in somatic cells of Drosophila melanogaster. This pairing can lead to transvection, which is a process by which the proximity of homologous genes can lead to a change in gene expression. At the yellow gene, transvection is the basis for several examples of intragenic complementation involving the enhancers of one allele acting in trans on the promoter of a pair...
متن کاملHomologous association of the Bithorax-Complex during embryogenesis: consequences for transvection in Drosophila melanogaster.
Transvection is the phenomenon by which the expression of a gene can be controlled by its homologous counterpart in trans, presumably due to pairing of alleles in diploid interphase cells. Transvection or trans-sensing phenomena have been reported for several loci in Drosophila, the most thoroughly studied of which is the Bithorax-Complex (BX-C). It is not known how early trans-sensing occurs n...
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ژورنال
عنوان ژورنال: Genetics
سال: 1997
ISSN: 1943-2631
DOI: 10.1093/genetics/146.3.919